Adverse Childhood Experiences Using Evidence to Advance Research Practice Policy and Prevention defines ACEs provides a summary of the past 20 years of ACEs research as well as provides guidance for the future directions for the field. It includes a review of the original ACEs Study definitions of ACEs and how ACEs are typically assessed. Other content includes a review of how ACEs are related to mental and physical health outcome the neurodevelopmental mechanisms linking ACEs to psychopathology sexual violence and sexual health outcomes and violence across the lifespan. Important and contemporary issues in the field like reconsidering how ACEs should be defined and assessed the appropriateness of routine ACEs screening thinking about ACEs from a public health and global perspective strategies for preventing ACEs understanding ACEs and traumainformed care and resilience and the importance of safe stable and nurturing environments for children are discussed. Adverse Childhood Experiences is a useful evidencebased resource for professionals working with children and families including physicians nurses social workers psychologists lawyers judges as well as public health leaders policy makers and government delegates. Reviews the past 20 years of ACEs researchExamines ACEs and mental and physical healthDiscusses the neurodevelopment mechanisms of ACEs and psychopathologyExamines ACEs and violence across the lifespanReconsiders the definition and assessment of ACEsExamines the issue of routine ACEs screeningDiscusses ACEs from a public health and global perspectiveSummarizes effective ACEs prevention traumainformed care and resilienceProvides recommendations for the future directions of the ACEs field