Dietary SupplementGluten FreeGI SupportMetabolism A proprietary, stable probiotic blend for everyday GI and weight management support. FloraMend Prime Probiotic supports a wide variety of health benefits, including GI support, weight management, seasonal allergy support, and immune function. Benefits GI Support, Metabolism FloraMend Prime Probiotic has the three characteristics of probiotic supplements needed in order to be optimally effective: (1) it's viable at room temperature; (2) it withstands stomach acid, so it's not degraded before it reaches the intestines; and (3) it's formulated to be distributed throughout the intestinal tract where it can adhere and reproduce. When taken daily, FloraMend helps promote a healthy gut microbiota that supports a wide variety of health benefits – from GI support, to weight management, to immune function. FloraMend is dairy-free and is provided as a convenient, once daily supplement. Mounting evidence supports the influence of the gut microbiome in weight management. What is the microbiome? It's all of the bacteria and other organisms that inhabit the gut, plus all of the genetic material and metabolites associated with this bacteria. Research indicates that the majority of flora in the gut is related to body weight. Animal and human studies demonstrate that lean individuals have different types and more diverse flora than obese individual. Alterations to the composition and metabolic capacity of the microbiome in obesity promote adiposity and influence metabolic processes in peripheral organs, such as the control of satiety in the brain, permeability of intestinal epithelium, with resulting inflammation, and the synthesis, storage, or metabolism of lipids in the adipose tissue, liver, and muscle. What probiotic organisms are in FloraMend Prime Probiotic? Lactobacillus gasseri This member of the Lactobacillus family is one of two species that human and animal data indicate have a supportive role in weight management. A human study on Lactobacillus gasseri found an average 4.6-percent reduction in visceral and subcutaneous adipose tissue with accompanying positive effects on body weight, waist circumference, and body mass index. Other common Lactobacillus organisms (such as L. acidophilus and L. fermentum) might actually improve energy utilization but might increase the risk of weight gain. Bifidobacterium (longum and bifidum) Bifidobacterium species are dominant in the mucus membrane that lines the large intestine. B. bifidum supports healthy gut immunity and helps maintain a beneficial balance of flora in the colon. It also supports the maintenance of a normal pH. Research has also found that B. bifidum and B. longum enhance the absorption of calcium, magnesium, and phosphorous. B. longum further supports immune function in the GI tract and bowel regularity. Healthy levels of Bifidobacterium might also provide protection against weight gain, particularly in childhood.