Section I: Immediate Cellular Response to Oxidative Stress and the Production of Second Messengers. - 1. Activation and Regulation of the Nitric Oxide-Cyclic GMP Signal Transduction Pathway by Oxidative Stress. - 2. Peroxynitrite and Cell Signaling. - 3. Nitric Oxide Signaling Through Mitochondrial Calcium Release. - 4. Phospholipase A2 Activation: An Early Manifestation of Oxidative Stress. - 5. Oxidant-Mediated Activation of Phospholipases C and D. - 6. Peroxide Tone in Eicosanoid Signaling. - 7. Protein Kinase C as a Sensor for Oxidative Stress in Tumor Promotion and Chemoprevention. - 8. Tyrosine Phosphorylation in Oxidative Stress. - 9. Reactive Oxygen Intermediates as Signaling Molecules Regulating Leukocyte Activation. - Section II: The Connection of Oxidative Induced Changes in Second Messengers and Transcription Factors with Activation of Gene Expression. - 10. Reactive Oxygen Species as Primary Signals and Second Messengers in the Activation of Transcription Factors. - 11. STAT Activation by Oxidative Stress. - 12. The Antioxidant Response Element. - 13. Oxyradicals as Signal Transducers. - Section III: Gene Expression in Response to Oxidative Stress. - 14. Modulation by Oxidants and Antioxidants of Signal Transduction and Smooth Muscle Cell Proliferation. - 15. The Role of Herne Oxygenase-1 in the Mammalian Stress Response: Molecular Aspects of Regulation and function. - 16. Induction of Gene Expression by Environmental Oxidants Associated With Inflammation Fibrogenesis and Carcinogenesis. - 17. Regulation of Glutathione Peroxidases. - 18. Gene Expression of DT-Diaphorase in Cancer Cells. Language: English